Author: Berkey, Melissa

Meet the PRAs – Darren Lee

Meet Darren Lee ’25, an OUR Peer Research Ambassador (PRA) majoring in Molecular & Cell Biology.

Meet the PRAs, picture of Darren, Peer Research Ambassador.What is the focus of your research?

Broadly, I’ve been interested in studying the interactions between organisms and their microbial communities. During my first year, I worked on a Holster Scholar project with Dr. Jonathan Klassen from MCB on fungus-growing ants, which cultivate a co-evolved fungus as their main food source. Work from the lab showed that the ants responded to chemical signals from pathogens, so we wanted to understand how this response was communicated between the ants and fungus. For my project, I evaluated how the ants’ behavior was affected by whether the fungus was alive or dead.

I’ve also worked in Dr. Joerg Graf’s lab, which studies the bacterial community of the European medicinal leech. The leech is an interesting model system since its digestive tract contains a relatively simple microbial community. We experimentally evolved Aeromonas veronii (one of the dominant community members) to look for genetic changes that might confer an advantage in colonizing the leech, then made a mutant A. veronii with the changes we observed to see if they affected the bacterium’s ability to colonize.

Since this summer, I’ve been in Dr. Yanjiao Zhou’s lab at UConn Health where I’ve done some data analysis for several ongoing studies in the lab. So far, I’ve worked on a study looking at a walnut diet in mice—walnuts have a unique nutrient profile that’s been linked to several positive health effects, so we were interested to see if long-term supplementation would lead to lasting changes in the mouse gut microbiome and metabolism.

Why did you get involved in research?

I’ve been a gardener for the longest time, and this has really made me appreciate the idea that there’s a whole world beneath our feet that’s intricately linked with the plants and animals that we can see. When I came to UConn, I was interested in doing microbiology research to pursue this curiosity, and I would say that although it’s taken me in an unexpected direction, I’ve had a really enriching experience so far! Continue reading

Meet the PRAs – Grace Vaidian

Meet Grace Vaidian ’24, an OUR Peer Research Ambassador (PRA) double majoring in Molecular & Cell Biology and Drugs, Disease, and Illness (individualized major) and minoring in Psychological Sciences.

Meet the PRAs, picture of Grace, Peer Research Ambassador.What is the focus of your research?

In the past I have done research on drug repurposing, which is the process of identifying new therapeutic uses for old / existing drugs. Currently I am involved in a project related to how personality may affect medication adherence. For this project I am working with Dr. Nathaniel Rickles from UConn’s Pharmacy department as well as St. Francis Hospital. Additionally, I work in Dr. John Salamone’s lab, which focuses on neuropsychopharmacology research.

Why did you get involved in research?

I was motivated to get involved in research because it allows me to have an outlet where I have the freedom to pursue my passions / interests. Research gives me a space to let my curiosity flow freely.

What advice would you give to aspiring student researchers?

The advice I would give to aspiring student researchers would be to take everything as a learning experience. You don’t have to be an expert on something to start pursuing research on that topic. Along the way you will learn the skills and information you need. Continue reading

Meet the PRAs – Fariha Fardin

Meet Fariha Fardin ’25, an OUR Peer Research Ambassador (PRA) majoring in Molecular & Cell Biology and minoring in Bioinformatics.

Meet the PRAs - picture of Fariha, Peer Research Ambassador.What is the focus of your research?

My research focuses on exploring muscle development and diseases of the musculoskeletal system through the use of mouse models and cell culture models. My current project, for which I received a SURF Award in the summer of 2023, delves into the effect of Acvr1R206H expression in muscle stem cells aka satellite cells on skeletal muscle regeneration, specifically in relation to the rare musculoskeletal disorder known as fibrodysplasia ossificans progressiva or FOP in short. By investigating these intricate mechanisms, I aim to deepen our understanding of FOP and contribute to advancements in the field of musculoskeletal research.

Why did you get involved in research?

My involvement in research began as a natural extension of my lifelong curiosity with science. From an early age, I found myself drawn to science fairs and thriving in my science classes. Throughout high school, I actively participated in science fairs and relished the opportunity to explore my scientific inquiries. Competing at both regional and state levels, I felt fortunate to delve deeper into my scientific questions. During high school, I was able to secure an internship with the U.S. Army, where I had the incredible opportunity to conduct research for a summer. This experience further ignited my interest in research, solidifying my passion for scientific investigation. Upon entering UConn, I was determined to continue pursuing research and honing my skills. In general, my unyielding passion for science and my unwavering curiosity propelled me to embark on the path of research. Continue reading

What Even Is Research? Common Questions and Misconceptions

By Darren Lee, Peer Research Ambassador

Picture of mascot Jonathan in a painterly style with text: Student Research Blog, What Even Is Research? Common Questions and Misconceptions. By PRA Darren.Another fall semester at UConn. Undoubtedly, it’s been a whirlwind of moving in, seeing new faces (or re-acquainting yourself with familiar ones), and settling into the rhythm of classes. By now, you’re most likely aware that many of your professors and TAs are involved in research in addition to just teaching. Whether they’re using their research to introduce themselves to the class, weaving references to it in between lecture slides, or complaining about deadlines (professors are human too!), they’ve probably made that fact abundantly clear. Without a doubt, research is an integral part of the work being done at this university. But what does this actually mean for you?

Most students’ first exposure to research is in college, so there’s naturally a lot of confusion and apprehension about it. Maybe you’re in awe of all the cool research being done at the university and you’re itching to work on your own project, but you don’t know how you can find a mentor or if you even can do research as an undergraduate. More likely, your eyes are glazing over as you wonder if you could ever get to that level of knowledge in your subject—research seems like an interesting way to get there, but it just seems so hard to get started. If those scenarios describe you at all, then you’ve come to the right place. In this blog post, we’ll be trying to dispel some common myths about research and help you understand what it’s like to be involved in research (Hint: you can do it and it can be really great!).

I’m just an undergraduate student. Are we even allowed to do research?

Yes! Many professors are happy to take in undergraduates who show a strong interest in their work. We even have an entire office at UConn (OUR!) dedicated to providing support and resources to undergraduates who want to get involved in research. Generally, there’s a really great culture surrounding undergraduate research here at UConn, and we’re always excited to have more students share in that! Continue reading

Lit Review Tips and Tricks

By Emma Beard, Peer Research Ambassador

As a STEM major, my biggest misconception about research was that I would spend more time at the lab bench than at my desk. I was surprised to find that for the first week of my time with the Health Research Program, I ran one or two experiments and then spent the rest of my time reading papers. At first, I felt like I wasn’t doing enough work since I wasn’t getting any data, but as I began to design my own experiments and brainstorm project directions, I realized just how important it is to learn from others’ projects. Reading research articles has been a constant throughout my time involved in undergraduate research, and through experience, I’ve discovered a few tricks that I would have loved to know when I was just getting started. While these tips are based on my experience in STEM research, hopefully one or two of these tips can help you as you begin your research journey, no matter the field!

1)  Write down every paper you read

I don’t know how many times I’ve thought to myself, “oh I read this in a paper,” and then realized I couldn’t remember which paper I found it in. Especially when I was first getting started, I read a lot of research papers to get introduced to the field, but thought about them in almost the same way as a textbook for a course where once I learned the material, I could move on. I didn’t realize how much I would need to refer back to papers later on, especially the materials and methods section for guidance on how to plan my own experiments.

Whether it’s a hand-written list kept in your lab notebook or typed out on your computer, write down the title and a few key points or relevant experimental techniques from each paper you read. I’m usually someone who prefers to handwrite rather than type (and did when I first started making my list), but for ease of reference, I’d recommend a typed list. Control/Command+F will be your best friend once you’ve read enough articles, and having the direct links available is extremely helpful. Continue reading

Breaking Up With Your Mentor

By Fraser McGurk, Peer Research Ambassador

Picture of the Avery Point campus lighthouse in a painterly style with text: Student Research Blog, Breaking Up With Your Mentor. By PRA Fraser.What do you do when it’s time to move on?

The journey through the world of research is as unpredictable as it is exciting. There is never one clear cut way to find your passion through research, and often this requires a bit of trial and error. On some occasions, someone’s first research mentor fits their every need, and that is great! However, that’s not the case for everyone, and sometimes it’s better to expand your horizons. There are a variety of reasons someone may want to diverge from their original research mentor. Whether it’s for convenience, disagreements, or just the passion to pursue something new, it’s OK to feel like you fit better somewhere else. But leaving your lab or mentor can be a daunting task. What if they react poorly? What if I lose a connection? Am I really making the right decision?

It is completely understandable for these thoughts to be rushing through your head, this is a big decision, and these conversations are never easy to have. But there are a few things that are crucial to know about breaking up with your mentor:

1) Do not feel guilty for leaving

When deciding to leave a lab, it can be easy to put it on yourself. Imposter syndrome is common for early-career researchers. Was I not smart enough for the lab? Am I just not made for research? What if I hurt their research by leaving? It’s normal to have second thoughts when you decide to leave. However, you should not feel guilty about your exit. You have every right to explore all the wonderful areas of research on campus, and you are not confined to one single research group for the entirety of your career. If a research group makes you feel guilty about exploring other options on campus, that is a glaring indicator of a toxic workplace that does not treat its students with respect. Continue reading

Meet the PRAs – Lina Layakoubi

Meet Lina Layakoubi ’24, an OUR Peer Research Ambassador (PRA) majoring in Biological Sciences.

Meet the PRAs - picture of Lina, Peer Research Ambassador.What is the focus of your research?

I work in the Menuz Lab in the PNB department. The main focus of my research is to understand the molecular and physiological mechanisms in which insects detect and seek out certain odors in their environment. My current project involves finding receptors involved in ammonia seeking behavior which is one way mosquitoes find human hosts.

Why did you get involved in research?

When I first started looking into research as a freshman, it seemed intimidating, confusing and otherwise unattainable. I spent my first year at UConn with completely online labs and the thought of jumping to a real lab was terrifying to me. As I learned more about molecular biology and physiology in my classes, I developed a passion that trumped this fear. I knew that my time as a biology major would not be complete without experiencing the world of research. Not only did joining a lab give me the chance to contribute to something beyond my textbooks but it also immersed me in a world rich with hands-on learning and new challenges. To me, research has been fun, exciting and crucial to my experience as a student. Looking forward, I can’t imagine research not being a part of my career! Continue reading

Meet the PRAs – Riley Beckham

Meet Riley Beckham ’24, an OUR Peer Research Ambassador (PRA) majoring in Electrical Engineering.

Meet the PRAs - picture of Riley, Peer Research Ambassador.What is the focus of your research?

I am interested in learning more about strengthening electrical grids and making them more resilient against extreme climate events. My recent work involves co-authoring a conference paper which examines how changing/shifting the amount of electricity supplied to an electrical grid during an extreme weather event can help reduce damage to the wider electrical network.

Why did you get involved in research?

I wanted to find a way to apply what I was learning in my engineering classes and find real world examples of the concepts I was being exposed to. Research seemed like a great place to start, and it seemed to me to be a low-risk way to explore my interests. A lot of my good friends were involved in research in their chosen fields, and they seemed to be getting a lot out of it, so I figured why not give it a try?  I enjoyed the idea of being able to ask questions without having any clue as to the answer: it was a liberating feeling, and one I credit with reinvigorating my passion for engineering in the latter half of my time at UConn. Continue reading

Semester Survival Hacks

By Anabelle Bergstrom, Peer Research Ambassador

Navigating research, academics, and extracurriculars can be daunting. Luckily, time management doesn’t need to be scary! At the beginning of every semester, I take some time to reflect on my study and schedule habits. That way, I am in tune with what works for me and what doesn’t. Every semester offers new experiences that change how I approach my responsibilities. I thought I would share some advice on what makes me successful, though it is important to note that just because these tips work for me, doesn’t mean they will work for you. Here are my top five study and schedule hacks to help you succeed this semester.

  1. Dedicated blocks of time– This tip helped me during one of my toughest semesters. Just like you would put a class or club into your schedule, put a block of time that is dedicated for studying. Do not schedule anything else during these times. This will allow your mind to become used to dedicated time to focus. Also, it will assist you in becoming more disciplined with your study habits.
  2. Disconnect – Turn off your phone and computer notifications. You may have heard this a million times, but I promise it makes a difference. Staying focused and present during your study time is a valuable skill to have. Having a distraction free environment will also help prepare you for exams.
  3. Take breaks – Remember to take a few moments when you are studying, and throughout the day, to ground yourself. Take a few deep breaths or drink water. It can even be helpful to set a timer for when to take a break while you are studying. As I mentioned, staying focused is key but remember that you are human. Studying for 4 hours straight can do more harm than good, so setting few minutes of time to go for a walk or grab a snack is beneficial.
  4. Surround yourself with people who understand – Part of surviving the semester is knowing when to throttle up and when to throttle down. You won’t be able to go to every girls night, party, or sporting event. Surrounding yourself with people who understand that you may need some nights to catch up on work or self-care will help immensely. Having a strong support system is key to surviving the semester.
  5. Listen to your body and mind – If you do not get anything else out of this blog post, at least take this piece of advice. Listen to yourself. You know yourself better than anyone. So, if you are feeling overwhelmed, allow yourself to set back and reset. This might look like a hike, a walk around town, or a long gym session. There is nothing more important, even academics, than making sure you are healthy and happy.

Continue reading

Meet the PRAs – Krithika Santhanam

Meet Krithika Santhanam ’25, an OUR Peer Research Ambassador (PRA) double majoring in Molecular & Cell Biology and Health Policy & Racial Disparities (individualized major).

Meet the PRAs, picture of Krithika, Peer Research Ambassador.What is the focus of your research?

The long bones of the adult arms and legs are originally completely made of cartilage. During embryonic development and adolescence, nearly all of the cartilage disappears and becomes replaced by bone through a process called endochondral ossification. The critical step of endochondral ossification is chondrocyte maturation; A stepwise differentiation program in which the chondrocytes that comprise the cartilage of the long bones proliferate, enlarge in size, and ultimately change into bone.

A key signal that promotes chondrocyte differentiation during maturation is the BMP (bone morphogenetic protein) pathway; A critical positive regulator of chondrocyte differentiation during maturation, however which individual BMP factor(s) mediate this role and their influence on promoting proliferation and/or stem cell behaviors are unknown. My project aims to identify a new chondrocyte population that emerges below the growth plate and into the bone marrow space by using markers to identify their properties. My project provides insight into how understanding signals that control the balance of stemness and differentiation may help restore articular cartilage loss in adults by stimulating cartilage growth.

Why did you get involved in research?

In all honesty, I got involved in research because it was something I saw high-achieving individuals pursing around me. As a Freshman, I wondered if I would be able to write a research proposal, present at a conference, and go through the experimental design process. I wanted to engage in this process to learn more about myself and try something new. Once I found a project I was passionate about, digging deeper into my work came naturally and going through difficult processes like applying for SURF, creating a poster, and experimental design allowed me to grow valuable skills of presentation, communication, and collaboration which is what I hoped for going into the experience. Continue reading