Project Mentor

Dr. Abhijit Deb Roy
Department of Center for Cell Analysis and Modeling and Cell Biology

Undergraduate Research Opportunity Description

Project Description	We are interested in interactions between different cytoskeleton (actin, microtubules and intermediate filaments) in cell motility. We apply molecular cloning, advanced fluorescent live cell imaging modalities and synthetic biology approaches to examine the molecular cross-talk between these cytoskeletal entities. Students working in our lab will learn to perform molecular biology techniques, mammalian cell culture, live cell microscopy and working with synthetic biology molecular tools to address fundamental questions in biological and biomedical context.
Project Direction	We are interested in the understanding the biochemical and biophysical pathways involved in directional cell motility, broadly in the context of angiogenesis and cancer metastasis. In the long term, we want to investigate relationships between extracellular environments and cell migratory responses, and identify the molecular signaling pathways that mediate the cellular responses.
Mentorship and Supervision	I will personally train the student in molecular biology techniques, mammalian cell culture and microscopy techniques. We will have a bi-weekly one-on-one meeting to discuss the project, experimental design and data analysis approaches. If needed, I will also train the student in basic coding required for data analyses.
Student Qualifications	We perform quantitative imaging techniques. An ideal candidate should be interested in applying quantitative approaches to understanding biological phenomena. Basic knowledge of coding, though not necessary, may be beneficial. A broad interest in biomedical sciences is useful; openness to learning new experimental and analyses approaches is very important.
Summer Schedule Options	Monday-Friday 9am through 6pm
Project Continuation	Fall 2025, Spring 2026
Academic Year Time Commitment	9 hours/week
Possible Thesis Project	Yes

Application

Submit an online application for this research opportunity at https://quest.uconn.edu/prog/HRPSU25-7. The application deadline is Monday, February 17, 2025.

This application requires a brief statement of research interests, and a brief statement of career interests. References should be available upon request.