HRP SU18-11: Research Opportunity with Dr. Leslie Loew

Project Mentor

Dr. Leslie Loew
R. D. Berlin Center for Cell Analysis and Modeling

Undergraduate Research Opportunity Description

Project Description The project would revolve around a unique software tool, developed here, called SpringSaLaD. It allows realistic modeling and simulation of complex multimolecular interactions in cells using structure-based molecular shapes and data on the rates of biochemical reactions. Depending on the student’s interests and skill set, the project would either involve using the software to build a model of a cell signaling pathway, or software engineering to enhance the features of SpringSaLaD.
Project Direction This modeling project is part of a broader effort to build and use computational tools to advance cell biology. Students may wish to go to vcell.org to see a broader context for this project.
Mentorship and Supervision I will meet with the student informally on a daily basis. We will have one more formal session at a set time each week. The student will also participate in our weekly lab meeting and present there several times over the course of the summer, where feedback will be offered by other members of the lab. At the end of the summer, the student will present in both a poster session and a CCAM Research in Progress meeting; these 2 events will include participation by all summer undergrad interns in CCAM labs.
Student Qualifications
  • Math up to differential equations.
  • For the modeling project: a physical chemistry or biophysics course.
  • For the software engineering project: programming in Java.

Minimum GPA: 3.5. Minimum Science GPA: 3.5.

Summer Schedule Options Research Dates: 9-10 full-time weeks to be scheduled between May 22 and August 17, 2018
Schedule: M-F, hours between 8am-6pm
Project Continuation Fall 2018, Spring 2019
Academic Year Time Commitment 6 hours/week
Possible Thesis Project Yes

Application

Submit an online application for this research opportunity using the form below. The application deadline is Friday, January 26, 2018.

This application requires a cover letter, a resume or CV, and an unofficial transcript.