Project Mentor

Dr. Douglas Oliver
Neuroscience

Undergraduate Research Opportunity Description

Project Description	We will use genetically modified mouse strains to investigate the neurons and circuitry of the inferior colliculus, a major nucleus in the auditory system. We are particularly interested in a mouse where MEK1 is overexpressed resulting in a much larger than normal inferior colliculus. The work includes genotyping mice (PCR), electrophysiological testing of hearing and sound processing (evoked potential or single cell recordings), as well as the morphological assessment of the neuronal network (microscopy and immunohistochemistry). We expect the student to assist in these experiments and animal husbandry. Depending on skill set and research interests, the student will be involved predominately in either histology or electrophysiology experiments.
Project Direction	Our lab investigates Neurobiology of Hearing, how the neurons and circuits in the auditory system process information about sound. We are interested both in the normal anatomy and physiology of this network as well as in the pathophysiological changes following noise trauma and blasts that lead to hearing loss and tinnitus. Our major focus is the auditory midbrain and its organization since that organization determines how information about sound reaches the auditory cortex.
Student Qualifications	An interest in neuroscience and previous coursework in neuroscience, physiological psychology, audiology, or biomedical engineering is required. The student has to be willing to participate in animal experiments. (IACUC animal training is mandatory). Prior knowledge of one of the methods used and a knowledge of the auditory system are highly desirable but not required. Minimum GPA: 3.0. Minimum Science GPA: 3.25.
Time Commitment	6-9 hours/week
Schedule Options	The schedule depends on the experiment the student participates in. For the electrophysiology, a block of at least 3h during the week is needed. Time and days will be coordinated with the other experimenters. For histology, weekend work is also possible.
Project Continuation	Summer 2017 and/or Fall 2017. Note: Summer research may involve participation in the Neuroscience in Salamanca, Spain study abroad program.
Possible Thesis Project	Yes

Application

Submit an online application for this research opportunity using the form below. The application deadline is Friday, January 6, 2017.

This application requires a cover letter, a resume or CV, and an unofficial transcript.