Project Mentor
Pedro Miura
Departments of Genetics and Genome Sciences
Undergraduate Research Opportunity Description
| Project Description | Genes are regulated post-transcriptionally through events targeting the 3’ Untranslated region of mRNAs. The project will involve using Drosophila melanogaster and ONT long read RNA sequencing to study gene regulation. In particular, the student will help determine how RNA binding proteins regulate Alternative cleavage and PolyAdenylation (APA) in the brain. |
| Project Direction | The student could extend into the academic year by performing computational analysis of the next generation sequencing data on APA regulation in Drosophila brain. In addition, wet lab experiments could be performed depending on time in lab (Farmington) availability. |
| Mentorship and Supervision | The student will have daily interactions and direct instruction from me and a senior lab member. Our aim is to provide an opportunity for focused research where the student has a chance to make or participate in a scientific discovery. Weekly one-on-one progress meetings between PI and trainee will take place. A final presentation will be made by the student in a group lab meeting. Formal mid and end of term evaluations will be made by the PI. |
| Student Qualifications | Interest in Biology and Research. Interest in learning bioinformatics/programming for biology. |
| Summer Schedule Options | Generally 9 am - 5 pm, Monday to Friday. Exceptions can be made. |
| Project Continuation | Fall 2026, Spring 2027 |
| Academic Year Time Commitment | 6, 9 hours/week |
| Possible Thesis Project | Yes |
Application
Submit an online application for this research opportunity at https://quest.uconn.edu/prog/HRP26-25. The application deadline is Monday, February 16, 2026.
This application requires a cover letter, a Resume or CV, a statement of research interests, and a statement of career interests. References should be available upon request.