Project Mentor
Dr. Samantha Fortin
Department of Medicine
Undergraduate Research Opportunity Description
| Project Description | The Fortin Lab is looking for undergraduate researchers to help conduct behavioral neuroscience research in rodent models to better understand how the brain regulates food intake and how pharmacotherapies for obesity (e.g. Ozempic) work and can be improved. Our current focus is directed at understanding the role of locus coeruleus glucagon-like peptide (GLP-1) and amylin receptors in modulating energy balance control. To do this, students will combines advanced behavioral assays with pharmacology and molecular imaging tools to determine the contribution of LC GLP-1 and amylin receptors to appetite, nausea, and autonomic physiology. Students will also contribute to general lab maintenance, animal husbandry, record keeping and data organization. |
| Project Direction | Given the role of the locus coeruleus in attention, arousal, and cognition, GLP-1 and amylin receptors in this region may influence behavioral and physiological processes far beyond energy balance. Future projects in the lab will explore the potential for obesity pharmacotherapies to improve cognitive dysfunction, with a particular focus on Alzheimer’s disease. |
| Mentorship and Supervision | Research assistants will will first receive structured onboarding in laboratory safety, animal handling, experimental design, data collection, and responsible conduct of research. We will use a team-based mentorship structure, which includes direct daily oversight from technicians and graduate students, with Dr. Fortin serving as the primary mentor responsible for long-term training goals, scientific development, and professional growth. Progress will be monitored through regularly scheduled meetings with Dr. Fortin, which will occur weekly during the initial training period and bi-weekly thereafter. These meetings will be used to review experimental progress, troubleshoot technical challenges, assess skill development, and set short- and long-term goals. The research assistant will also participate in lab meetings, where data presentation and scientific discussion will allow for ongoing evaluation of conceptual understanding and communication skills. |
| Student Qualifications | Interest and academic background in: neuroscience, physiology, pharmacology, or a related field.
Experience/skills (preferred, not required): rodent handling, basic molecular biology techniques, microscopy experience, data organization and analysis. Professional qualities: reliability, organization, attention to detail, self-motivated, strong communication skills |
| Summer Schedule Options | M-F: 9-5 with occasional weekend obligations (1-2hr/shift) |
| Project Continuation | Fall 2026, Spring 2027 |
| Academic Year Time Commitment | 3 6 9 hours/week |
| Possible Thesis Project | Yes |
Application
Submit an online application for this research opportunity at https://quest.uconn.edu/prog/HRPSU26-11. The application deadline is Monday, February 16, 2026.
This application requires a resume or CV, GPA, a brief statement of research interests, and a brief statement of career interests. References should be available upon request.