Project Mentor

Dr. Blanka Rogina
Genetics & Genome Sciences

Undergraduate Research Opportunity Description

Project Description	The Drosophila I’m Not Dead Yet (INDY) gene encodes a plasma membrane citrate transporter. We have reported that reduction in the Indy gene activity in flies modulates metabolism and extends longevity in a way that has been compared to caloric restriction. Our Indy flies live longer and are protected from the negative effects of high calorie diet. We also reported that INDY reduction in fly intestine preserves intestinal stem cell (ISC) homeostasis. We are currently investigating effect of different calorie content of food on ISC proliferation and how Indy reduction affects this response.
Project Direction	Our studies can contribute to our knowledge of the mechanisms how high calorie diet contribute to weight gain. We will also examine if reduced INDY levels could be protective for this weight gain.
Student Qualifications	– Interest in research, genetics, and model organisms. – Completed or in progress genetics classes. – Interest in applying to PhD programs or Medical/Dental School.
Time Commitment	6-9 hours/week
Schedule Options	Mondays, Tuesdays, Wednesdays after 9:00 AM. Thursdays & Fridays after 10:00 AM.
Project Continuation	Summer 2017 and/or Fall 2017
Possible Thesis Project	Yes

Application

Submit an online application for this research opportunity using the form below. The application deadline is Friday, January 6, 2017.

This application requires a cover letter, a resume or CV, an unofficial transcript, and a brief statement of career interests. You must also arrange to have one letter of recommendation sent to Dr. Rogina by January 6th (see details below).